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Nova痢疾阿米巴检测试剂盒

Nova痢疾阿米巴检测试剂盒

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痢疾阿米巴的病原体是entamebosis发生。痢疾阿米巴的营养阶段(营养体)住在大肠,形成包绕的阶段(囊肿)与粪便排泄。
营养体可以穿透肠壁,侵入肝脏及其他器官产生临床amebosis形式,Z常见的肠道amebosis和肝amebosis(阿米巴肝脓肿)。
临床症状可以开发Z早在感染后2 - 4周或无症状后几个月,甚至几年的时间。

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痢疾阿米巴

痢疾阿米巴的病原体是entamebosis发生。痢疾阿米巴的营养阶段(营养体)住在大肠,形成包绕的阶段(囊肿)与粪便排泄。

营养体可以穿透肠壁,侵入肝脏及其他器官产生临床amebosis形式,zui常见的肠道amebosis和肝amebosis(阿米巴肝脓肿)

临床症状可以开发zui早在感染后2 - 4周或无症状后几个月,甚至几年的时间。

以下肠道形式出现:

  • 入侵肠道形态结果肠壁的病原体的入侵和反映了大肠疾病。急性疾病通常开始于腹部不适,发作的腹泻持续时间不同,起初糊状的增加黏液状的,包括一旦凳子。自然可以缓解症状,但经常再犯慢性结肠炎的发展,可以持续几个月,甚至几年。
  • 在大多数情况下,无症状的肠道形成运行无症状。随便感染诊断出患有凳子上测试(营养体??更频繁的囊肿在凳子上)。
  • Extraintestinal形式出现在ca。30%的感染。zui常见的形式是所谓的?肝脓肿吗?,在肝阿米巴原虫的传播。肝脓肿引起弛张热(有时高),上腹痛、肝肿大、高程的隔膜、全身无力等症状。大不及时治疗肝脓肿通常是致命的。

痢疾阿米巴感染发生在世界范围内,普遍在温暖的国家。在流行地区,在非洲、亚洲和南美洲70 - 90%的人口可以痢疾阿米巴的载体。感染是由囊肿从一个人传播到另一个由于传播成熟的囊肿和受污染的食品(果蔬),饮用水或粪便污染的手。苍蝇和蟑螂可以从粪便作为中介,囊肿excretor的食物。每年新发病例的数量估计在4800万年,约有70 000致命的结果(,1998)。

物种

感染的机制

症状

并发症

诊断

痢疾阿米巴

口周围的摄入、饮用水、食物

没有超过90%(无症状,肠道形式)出现大便,腹泻、败血症

腹部出血、结肠炎、肝脓肿、腹膜炎

显微镜临床血清学方法(超音波,电脑断层扫描等)

感染的诊断则需要通过:

  • 显微镜:确定寄生虫在凳子上
  • 血清学:特定抗体基于ELISA-technique的决心

NovaLisa?痢疾阿米巴免疫球蛋白ELISA:

NovaLisa?痢疾阿米巴免疫球蛋白ELISA用于定性测定IgG-class抗体痢疾阿米巴在人类血清或血浆(柠檬酸)

抗原:

纯化痢疾阿米巴Trophozoit抗原

具体的性能特征:

 

Intraassay

Interassay

灵敏度

特异性

 

n

的意思是

CV %

n

目的

CV %

 

 

免疫球蛋白

7

0.609

2.1

6

0.604

3.9

> 95%

> 95%

订单信息:

ELISA

的数量决定

产品编号

痢疾免疫球蛋白

96

ENTG0140

 

 

 

 

Entamoeba histolytica

Entamoeba histolytica is the causative agent of the worldwide occurring entamebosis. The vegetative stages (trophozoites) of Entamoeba histolytica live in the large intestine and form encysted stages (cysts) that are excreted with feces.

The trophozoites can penetrate into the intestinal wall and invade the liver and other organs to produce clinical forms of amebosis, most frequently intestinal amebosis and hepatic amebosis (amoebic liver abscess).

Clinical symptoms can develop as early as 2-4 weeks after infection or after asymptomatic periods of months or even years.

The following intestinal forms occur:

  • The invasive intestinal form results from the invasion of the intestinal wall by the pathogen and reflects large intestine disease. The acute disease usually begins with abdominal discomfort and episodes of diarrhea of varying duration, at first mushy the increasing mucoid, including blood-tinged stool. The symptoms may abate spontaneously, but fairly often a recidivating chronic colitis develops that can last for months or even years.
  • In most cases the asymptomatic intestinal form runs asymptomatic. The infection is casually diagnosed with a stool test (Trophozoites and more frequent cysts in stool).
  • Extraintestinal forms appear in ca. 30 % of all infections. The most frequent form is the so called ?liver abscess?, the spread of amoebas in liver. The liver abscess causes remittent fever (sometimes high), upper abdominal pain, liver enlargement, elevation of the diaphragm, general weakness and other symptoms. Large liver abscesses that are not treated in time are often lethal.

Infections of Entamoeba histolytica occur worldwide, prevalent in warmer countries. In endemic areas in Africa, Asia and Central and South America up to 70-90% of the population can be carriers of Entamoeba histolytica. The infection is transmitted by cysts from one human to another due to transmission of mature cysts with contaminated foods (fruit vegetables), drinking water or fecally contaminated hands. Flies and cockroaches can function as intermediaries by carrying cysts from the feces of an excretor to foods. Worldwide the annual number of new cases is estimated at 48 million, with about 70 000 lethal outcomes (WHO, 1998).

Species

Mechanism of Infection

Symptoms

Complications

Diagnostic

Entamoeba histolytica

Peroral ingestion,drinking water, foods

With more than 90% no (asymptomatic, intestinal form)blood-tinged stools, diarrhea, sepsis

Abdominal bleeding, colitis,liver abscess, peritonitis

Microscopy Serology Clinical methods(Ultrasound, computer tomography, etc.)

Infections may be diagnosed by:

  • Microscopy: Determination of parasites in stool
  • Serology: Determination of specific antibodies based on the ELISA-technique 

NovaLisa? Entamoeba histolytica IgG ELISA:

The NovaLisa? Entamoeba histolytica IgG ELISA is intended for the qualitative determination of IgG-class antibodies against Entamoeba histolytica in human serum or plasma (citrate). 

Antigens:

Purified Entamoeba histolytica Trophozoit antigens

Specific performance characteristics:

 

Intraassay

Interassay

Sensitivity

Specificity

 

n

Mean

CV%

n

Meam

CV%

 

 

IgG

7

0.609

2.1

6

0.604

3.9

>95%

>95%

Order information:

ELISA

Number of Determinations

Product Number

Entamoeba IgG

96

ENTG0140

 

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