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Rickettsia 2-Antigen MIF IgG kit
广州健仑生物科技有限公司
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【公司名称】 广州健仑生物科技有限公司
【】 杨永汉
【】
【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-3室
【企业文化】
这项研究发表于《PLoS ONE》杂志上,Kumar,以及合著者、MU兽医医学院的副教授杰弗里·布莱恩,使用称为ODDHSL的细菌通讯分子用来治疗在培养基中生长的人胰腺癌细胞。经过治疗后,人胰腺癌细胞停止繁殖,未能迁移并开始死亡。
“我们之所以使用胰腺癌细胞,是因为这些细胞是发生在人体内zui强大的,侵袭性的以及难以杀灭的癌细胞,” Kumar说。“为了表明,这种分子不仅可以阻止癌细胞扩散,而且实际上也会导致它们死亡,这是非常令人兴奋的。因为这个治疗方法表明,其很有希望应用于像胰腺癌这种侵袭性的癌症。我们相信它也可用于其他类型的癌细胞,以及我们实验室正在其他类型的癌细胞中测试该治疗方法。”
Kumar说,他研究的下一步是在动物和人体试验发生前,寻找一个更有效的方式将该分子引入癌细胞中。
“现在,我们zui大的挑战是,寻找一种有效的方式引入该分子,” Kumar说。“在这个时候,我们只能够用这种分子在实验室中治疗癌细胞。现在,我们使用一个更好的方法来处理动物癌症,看看这个治疗是否真的有效。本研究的早期结果是有希望的。如果进一步的研究,包括动物实验,都成功后,下一步是将这个方法应用于临床试验。”
The study, published in PLoS ONE, by Kumar and co-author Jeffrey Bryan, an associate professor at MU Veterinary Medical School, uses a bacterial communication molecule called ODDHSL to treat human pancreas that grows in culture cancer cell. After treatment, human pancreatic cancer cells stop multiplying, fail to migrate and begin to die.
"The reason we use pancreatic cancer is because these cells are the most powerful, aggressive and hard-to-kill cancer in the body," Kumar said. "It's very exciting to show that this molecule not only stops the spread of cancer cells but actually causes them to die, as this treatment shows promise for promising invasiveness like pancreatic cancer We believe it is also available for other types of cancer cells and our laboratory is testing the treatment in other types of cancer cells. "
Kumar said the next step in his research is to find a more effective way to introduce the molecule into cancer cells before animal and human trials occur.
"Now, our biggest challenge is to find an effective way to introduce that molecule," Kumar said. "At this point, we were only able to use this molecule to treat cancer cells in the laboratory, and now we use a better approach to treating animal cancers and see if the treatment is really effective. The early results of this study were Hopefully, if further research, including animal experiments, is successful, the next step is to apply the method to clinical trials. "