待测抗体样本释放剂

广州健仑生物科技有限公司

（广州健仑生物科技有限公司是集研制开发、销售、服务于一体的优良企业,公司产品涉及临床快速诊断试剂、食品安全检测试剂，违禁品快速检测，动物疾病防疫检测试剂，免疫诊断试剂、临床血液学和体液学检验试剂、微生物检验试剂、分子生物学检验试剂、临床生化试剂、有机试剂等众多领域，同时核心代理Panbio、FOCUS、Qiagen、IBL、CORTEZ、Fuller、Inbios、BinaxNOW、LumuQuick、日本富士、日本生研等多家有名诊断产品集团公司产品，致力于为商检单位、疾病预防控制中心、海关出入境检疫局、卫生防疫单位,缉毒系统，戒毒中心，检验检疫单位、生化企业、科研院所、医疗机构等机构与行业提供*、高品质的产品服务。此外，本公司还开展食品、卫生、环境、药品等多方面的第三方检测服务。）

【产品名称】样本释放剂

【包装规格】20测试/盒 （溶液I:20×1 Test/瓶；溶液II:20 Test/瓶）         □

50测试/盒 （溶液I:50×1 Test/瓶；溶液II:50 Test/瓶X 1 ）    □

             100测试/盒 （溶液I:100×1 Test/瓶；溶液II:50 Test/瓶X 2）   □

【预期用途】

用于待测致敏红细胞样本的预处理，使致敏红细胞样本中的待测抗体从与细胞结合的状态中解离释放出来。以便于使用体外诊断试剂或仪器对待测抗体进行检测。

【检验原理】

红细胞上的抗原与血清中抗体在适合条件下发生致敏，这种结合在一定条件下是可逆的。将已致敏的红细胞悬浮于低pH值的甘氨酸溶液中，抗体蛋白又可以从结合的红细胞上解离释放出来。离心取上清解离的放散液，此液中含有从红细胞表面解离释放出来的抗体蛋白，经Tris缓冲液调节pH至中性后此上清放散液可用于相关抗体的检测和鉴定；而解离释放后的红细胞经洗涤后可用于血型定型、自身抗体的吸收等。

【主要组成成份】

1.溶液I：主要组分为甘氨酸(C₂H₅NO₂)，氯化钠(NaCl)。

2.溶液II：主要组分为Tris碱，指示剂。   

【储存条件及有效期】                  

常温（10～30℃）储存，有效期1年。试剂开瓶后在常温（10～30℃）条件下可储存6个月。

【样本要求】

新鲜或2～8℃保存不超过72小时的抗凝血样。

待测抗体样本释放剂

我司还提供其它进口或国产试剂盒：登革热、疟疾、西尼罗河、立克次体、无形体、蜱虫、恙虫、利什曼原虫、RK39、汉坦病毒、深林脑炎、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【产品介绍】

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【公司名称】 广州健仑生物科技有限公司
【】    杨永汉 
【】 
【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-3室
【企业文化】

这些毛细血管网下行到结节部汇集形成数条垂体门微静脉，它们下行进入远侧部，再度形成窦状毛细血管网，称第二级毛细血管网。垂体门微静脉及其两端的毛细血管网共同构成垂体门脉系统（hypophyseal portal system）。远侧部的毛细血管zui后汇集成小静脉注入垂体周围的静脉窦。这是1930年代确立的经典垂体血流模式“自上而下”的概念，阐明了下丘脑控制垂体功能的基本机制。此后又通过新技术的应用和研究，对垂体的血流模式提出了新见解，认为远侧部的血液可输入神经垂体的漏斗，然后经毛细血管回流入下丘脑；也可流入神经部，再逆向流入漏斗，然后再循环到远侧部或下丘脑，构成整个垂体血流在垂体内的循环流动。[1]  [4-5] 
下丘脑
下丘脑神前区和结节区（弓状核等）的一些神经元具有内分泌功能，称为神经内分泌细胞，细胞的轴突伸至垂体漏斗。细胞合成的多种激素经轴突释放入漏斗处的*级毛细血管网内，继而经垂体门微静脉输至远侧部的第二级毛细血管网。这些激素分别调节远侧部各种腺细胞的分泌活动（图11－12）。其中对腺细胞分泌起促进作用的激素，称释放激素（releasing hormone,RH）。对腺细胞起抑制作用起抑制作用的激素，则称为释放抑制激素（release inhibiting hormone,RIH）目前已知的释放激素有：生长激素释放激素（GRH）、催乳激素释放激素（PRH）、促甲状腺激素释放激素（TRH）、促性腺激素释放激素（GnRH）、促肾上腺皮质激素释放激素（CRH）及黑素细胞刺激素释放激素（MSRH）等。释放抑制激素有：生长激素释放抑制激素（或称生长抑素，SOM）、催乳激素释放抑制激素（PIH）和黑素细胞刺激素释放抑制激素（MSIH）等。由此可见，下丘脑通过所产生的释放激素和释放抑制激素，经垂体门脉系统，调节腺垂体内各种细胞的分泌活动；病毒而，将此称为下丘脑腺垂体系。反之，腺垂体产生的各种激素又可通过垂体血液环流，到达下丘脑，反馈影响其功能活动
传统认为，垂体前叶仅有少量自主神经纤维，支配前叶内血管的舒缩；而腺细胞的分泌活动则主要受下丘脑各种激素的调节，并无神经的直接支配。
These capillary network down to the nodules converge to form a few pituitary-portal venules, they descend into the distal part of the re-formation of sinusoidal capillary network, said the second capillary network. The hypophyseal portal vein is formed by the pituitary gland microvessels and capillary networks at both ends of the pituitary gland. The distal part of the capillaries converge into a small vein into the periphery of the pituitary sinus. This is the concept of the "top-down" classic pituitary flow model established in the 1930s, illustrating the underlying mechanism by which the hypothalamus controls pituitary function. Then through the application of new technologies and research, put forward new ideas on the pituitary blood flow model, that the distal part of the blood can be fed into the funnel of the pituitary gland and then back into the hypothalamus through the capillaries; can also flow into the nerve, and then Reverse inflow funnel, and then recycle to the distal part or the hypothalamus, constitute the entire pituitary blood flow in the pituitary circulation. [1] [4-5]
Hypothalamus
Some neurons in the hypothalamus prefrontal and nodal regions (arcuate nucleus, etc.) have endocrine functions, called neuroendocrine cells, and axons extend to the pituitary funnel. A variety of hormones synthesized by cells are released into the first capillary network at the funnel and then to the second capillary network of the distal part via the pyloric vein. These hormones regulate the secretory activity of various glandular cells distal (Figure 11-12). Among them, the hormone that promotes the secretion of glandular cells is called releasing hormone (RH). The hormone that inhibits glandular cells is known as release inhibiting hormone (RIH). Known releasing hormones are: growth hormone releasing hormone (GRH), prolactin releasing hormone (PRH), thyrotropin Hormone releasing hormone (TRH), gonadotropin releasing hormone (GnRH), corticotropin releasing hormone (CRH) and melanocyte stimulating hormone releasing hormone (MSRH) and so on. Release inhibitory hormones are: somatostatin (or somatostatin, SOM), prolactin releasing hormone (PIH) and melanocyte stimulating hormone releasing hormone (MSIH) and so on. Thus, the hypothalamus through the release of hormones and release of inhibitory hormone, the pituitary portal system, regulating the secretion of various cells in the pituitary gland activity; the virus, this will be called the hypothalamic pituitary gland system. Conversely, the various hormones produced by the pituitary gland and through the pituitary blood circulation, reaching the hypothalamus, feedback affect its functional activity
Traditionally, there was only a small amount of autonomic nerve fibers in the anterior pituitary, controlling the contraction and contraction of blood vessels in the anterior lobe. The secretory activity of glandular cells was mainly regulated by various hormones in the hypothalamus without any direct control of nerves.