沙眼衣原体诊断试剂盒（ELISA法)

广州健仑生物科技有限公司

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沙眼衣原体诊断试剂盒（ELISA法)

沙眼衣原体诊断试剂盒（ELISA法)

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【公司名称】 广州健仑生物科技有限公司
【】    杨永汉 
【】 
【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-3室
【企业文化】

虫卵在血管内成熟，内含毛蚴，毛蚴分泌溶细胞物质，透过卵壳入肠粘膜，破坏血管壁并使周围肠粘膜组织破溃与坏死。由于肠的蠕动，腹腔内压力与血管内压力的增高，使虫卵与坏死组织落入肠腔，随粪便排出体外。虫卵入水后在20～30℃经12～24小时即孵化出毛蚴，在水中游动的毛蚴1～2天内，遇到钉螺（中间宿主）即主动侵入，在螺体肝、淋巴腔内、发育为母胞蚴、子胞蚴，再经5～7周形成大量尾蚴，逐渐逸出螺体外，尾蚴入水或逸出于河边或岸上青草露水中。终宿主接触水中尾蚴时，尾蚴吸附于宿主的皮肤，利用分泌的溶蛋白酶溶解皮肤组织，脱去尾部进入表皮变为童虫。童虫侵入真皮层的淋巴管或微小血管至静脉系统，随血流至右心、肺、左心进入体循环，或由肺穿至胸腔，通过横膈入腹腔。约经4天后到达肠系膜静脉，并随血流移至肝内门脉系统，初步发育后再回到肠系膜静脉中定居，在此，雌雄合抱，性成熟，产卵。从尾蚴经皮肤感染至交配产卵zui短需23～35天，一般为30天左右。成虫在宿主体内生存2～5年即死亡，有的成虫在病人体内可存活30年以上。流行病学编辑本病流行于中国、日本、菲律宾等地。中国则见于长江流域和长江以南的十三个省、市、自治区的三百三十三个县市。中国台湾的日本血吸虫未见有人体感染。本病的流行必须具备以下三个环节：（一）传染涁日本血吸虫患者的粪便中含有活卵，为本病主要传染源。船户粪便直接下河以及居民在河边洗刷马桶是水源被污染的主要原因。随地大便，河边粪坑及用未处理的新鲜粪便施肥，被雨水冲入河流，造成水源污染。病畜（牛、羊、犬）及鼠等含有虫卵，随粪便排出，污染水源。钉螺：为血吸虫的*中间宿主，是本病传染过程的主要环节。钉螺喜栖在近水岸边，在湖沼地区及芦滩洼地上zui多。在平原地区孳生于土质肥沃，杂草丛生，水流缓慢的潮湿荫蔽地区，沟渠zui多，岸边次之，稻田中zui少。钉螺感染率以秋季为zui高。（二）传播途径 主要通过皮肤，粘膜与疫水接触受染。多通过游泳洗澡、洗衣、洗菜、淘米、捕鱼捉蟹，赤足经过钉螺受染区等方式感染。尾蚴侵入的数量与皮肤暴露面积。

Eggs mature in the blood vessels, contain hairs, and secrete cell-soluble substances in the hairs, and enter the intestinal mucosa through the egg shells, destroying the blood vessel walls and causing ulceration and necrosis of the surrounding intestinal mucosa. Due to the peristalsis of the intestine, the pressure in the abdominal cavity and the pressure in the blood vessel increase, the eggs and necrotic tissues fall into the intestine and are excreted with the feces. After the eggs enter the water, the hairs are hatched at 20 to 30°C for 12 to 24 hours. Within 1 to 2 days of the furs swimming in the water, snails (intermediate hosts) actively invade, in the snail's liver and lymphatic cavity. It develops into a mother cell and a daughter cell, and after 5 to 7 weeks, it forms a large number of cercariae and gradually escapes the spleen. The cercariae enters the water or escapes from the river or on the grassy dew. When the final host contacts the tail scorpion in the water, the cercariae are absorbed on the host's skin, and the secreted lytic protein dissolves the skin tissue and removes the tail and enters the epidermis into a schistosome. The schistosomiasis invades the lymphatic vessels or tiny blood vessels of the dermis to the venous system, and flows into the right heart, lungs, and left heart into the systemic circulation, or from the lungs to the thoracic cavity, through the diaphragm into the abdominal cavity. After about 4 days, it reached the mesenteric vein and moved to the intrahepatic portal system with the blood flow. After initial development, it returned to the mesenteric vein where it settled. Here, the male and female copulate, sexually mature, and lay eggs. It takes 23 to 35 days for the shortest period from the cercaria infection to the mating and spawning, usually about 30 days. Adults live within the host for 2 to 5 years and die, and some adults can survive in patients for more than 30 years. Epidemiology Edit this disease is prevalent in China, Japan, the Philippines and other places. China is found in 133 rivers in the Yangtze River Valley and 13 provinces, cities, and autonomous regions south of the Yangtze River. There was no human infection with schistosoma japonicum in Taiwan. The epidemic of this disease must have the following three links: (1) The feces of patients infected with schistosomiasis contain live eggs, which is the main source of infection of the disease. The main reason why water is contaminated is the fact that the ship's manure goes directly to the river and that residents wash toilets along the river. Defecation everywhere, riverside pits and fertilizing with untreated fresh manure, was flushed into rivers by rain, causing water pollution. Diseased animals (cattle, sheep, and dogs) and rats contain eggs, which are excreted in the faeces and pollute water sources. Snails: The only intermediate host for schistosomiasis is the main link in the process of infection. Snails hi habitat in the water near the shore, in the lake area and Lu beach depression most. In the plain area, it was born in a wet and shaded area with fertile soil, weeds, and slow water flow. The ditches were the most, followed by the banks, and the least in the rice fields. The snail infection rate is highest in autumn. (b) Routes of transmission The skin and mucous membranes are mainly affected by infection with infected water. More bathing, washing, washing vegetables, washing rice, catching crabs by fishing, barefoot infection by infected areas such as snails. The number of cercariae invasion and skin exposed area